䀡碼源𧵑病安佳𣙪

{{1000排基本}}
{{Infobox medical condition (new)
 |name          = 病安佳𣙪
 |image         = Brain-ALZH.png             
 |caption       = 表圖𨋤逞腦老化通常（債）貝腦𧵑𠊛病安佳𣙪（沛）和指𦋦仍點恪憢𠁹𠄩場合。
 |pronounce     = ˈaltshʌɪməz
 |field         = [[科神經|神經]]
 |synonyms      = 安佳𣙪
 |symptoms      = 𧁷汝吏仍事𧵆低、[[𠅍言語進展原發|問題衛言語]]、[[定向（心神）|𠅍方向]]、[[𠊝𢷮心狀]]失常
 |complications =
 |onset         = 65歲𧿨𨖲<ref name=Mend2012/>
 |duration      = 𥹰𨱾<ref name=WHO2020/>
 |causes        =（參考自各博士、醫學和各專家）：染毒神經自{{r|微咄|virus}}、或各質毒害如水銀。態慣𠸙固害咮腦如役接觸𥹰𨱾貝設備電子或𡗉原因恪固連關。外𦋦、可能恪如沉感、用質激刺、茦... 拱固體羅原因𧵑根病。
 |risks         = [[遺傳學|遺傳]]、[[震傷]], [[𦇒亂沉感正|沉感]], [[高血壓]]<ref name=BMJ2009/><ref name=Lancet2011>{{chú thích tạp chí |vauthors=Ballard C, Gauthier S, Corbett A, Brayne C, Aarsland D, Jones E |title=Alzheimer's disease |journal=Lancet |volume=377 |issue=9770 |pages=1019–31 |date=March 2011 |pmid=21371747 |doi=10.1016/S0140-6736(10)61349-9 |s2cid=20893019}}</ref>
 |diagnosis     = 𢭸𨕭兆症和[[檢查認識]]𨍦欺類除各可能<ref name=NICE2014Diag/>
 |differential  = 老化通常<ref name=BMJ2009/>
 |prevention    =（參考自專家）：學添言語外㗂媄𤯰、補充𣹓𨁥營養固利咮腦部、練智腦、限制𨢇啤、各質激刺如痲醉和咖啡、空識𣅘過10h、和咹𡗉蔞榘果𣛤𣘃。
 |treatment     =
 |medication    = {{r|[[茦抑制阿嗤村棍離涅疏絲䇴]]|Thuốc ức chế Acetylcholinesterase}}、 [[質對抗受體NMDA]]（利益空當計）<ref name=Pres2012>{{chú thích tạp chí |author=Commission de la transparence |title=Drugs for Alzheimer's disease: best avoided. No therapeutic advantage |journal=Prescrire International |volume=21 |issue=128 |page=150 |date=June 2012 |pmid=22822592 |trans-title=Drugs for Alzheimer's disease: best avoided. No therapeutic advantage}}</ref>
 |prognosis     = 𠸙添得—9𢆥<ref name=NEJM2010/>
 |frequency     = 29,8兆（2015）<ref name=GBD2015Pre/>
 |deaths        = 1,9兆（悉哿病[[𠅍智]]、 2015）<ref name=GBD2015De/>
}}
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'''病安佳𣙪'''（Bệnh Alzheimer）、或單簡羅{{r|'''安佳𣙪'''|Alzheimer}}、羅沒[[退化神經|病退化神經]]常起發徐徐和𣈜更𧿨𢧚嚴重。<ref name="WHO2020">{{chú thích web|title=Dementia Fact sheet|date=September 2020|publisher=World Health Organization|url=https://www.who.int/en/news-room/fact-sheets/detail/dementia}}</ref>病佔60—70%原因引𦤾[[衰减智𢖵|𠅍智]]。<ref name="WHO2020" />兆症班頭普遍一羅役[[智𢖵𠦯限|𧁷汝吏仍事件𧵆低]]。<ref name="BMJ2009">{{chú thích tạp chí|vauthors=Burns A, Iliffe S|s2cid=8570146|title=Alzheimer's disease|journal=BMJ|volume=338|page=b158|date=February 2009|pmid=19196745|doi=10.1136/bmj.b158}}</ref>欺病𧿨𨤼、𠊛病固體[[𠅍言語進展原發|﨤𧁷䘜衛言語]]、[[定向（心神）|𠅍方向]]（包𠁟役易𠫾落）、[[𠊝𢷮心狀]]失常、𠅍[[動機（心理學）|動力]]、𠬃𠾦本身和﨤[[行為託識|問題衛行為]]。<ref name="BMJ2009" />欺情狀𧵑𠊛病醜𠫾、戶常收𨉟塊𠊛親和社會。<ref name="BMJ2009" />夤夤、𠊛病𠅍各職能𧵑肌體和𡳜窮羅死亡。<ref name="NIA2019">{{chú thích web|title=Alzheimer's Disease Fact Sheet|url=https://www.nia.nih.gov/health/alzheimers-disease-fact-sheet|website=National Institute on Aging|access-date=ngày 25 tháng 1 năm 2021|language=en}}</ref>默𢂎速度發展𧵑病固體恪憢、𠊛病常𠸙添得自3𦤾9𢆥𨍦欺得診斷縸病。<ref name="NEJM2010">{{chú thích tạp chí|vauthors=Querfurth HW, LaFerla FM|s2cid=205115756|title=Alzheimer's disease|journal=The New England Journal of Medicine|volume=362|issue=4|pages=329–44|date=January 2010|pmid=20107219|doi=10.1056/NEJMra0909142}}</ref><ref>{{chú thích tạp chí|vauthors=Todd S, Barr S, Roberts M, Passmore AP|title=Survival in dementia and predictors of mortality: a review|journal=International Journal of Geriatric Psychiatry|volume=28|issue=11|pages=1109–24|date=November 2013|pmid=23526458|doi=10.1002/gps.3946|s2cid=25445595}}</ref>

<!-- Nguyên nhân, chẩn đoán và phòng ngừa -->原因𧵑根病現刎當得尋曉、和現在刎𣗓𠓑𫜵勢芇𦓡沒𠊛吏固體縸根病。仍𢭸蹺沒數假說𧵑博士𠊝替、原因固體由役汵各質毒𥹰𨱾自役咹㳹、識𣈘連續、少𥄬、少𧖱𥹰𣈜、染毒如遇毒[[鈘]]、[[吉眉]]、...<ref name="Long" /><ref name="NIA2021">{{chú thích web|title=Study reveals how APOE4 gene may increase risk for dementia|url=https://www.nia.nih.gov/news/study-reveals-how-apoe4-gene-may-increase-risk-dementia|website=National Institute on Aging|access-date=ngày 17 tháng 3 năm 2021|language=en}}</ref>外𦋦、群固各要素危機恪得咮羅固可能𨠳病恪、包𠁟前史[[震傷頭]]、[[沉感臨床]]和[[高血壓]]。<ref name="BMJ2009" />過程𨠳𦋦病主要固關係貝各{{r|[[𤗖諳眉雷]]|mảng amyloid}}、[[各盎𦇒𥾘神經]]拱如事𠅍[[蚩納|結𦀼𦀨燉]]𪚚[[腦𠊛|腦部]]。<ref name="NIA2019" />固體診斷安佳𣙪沒格相對𢭸𨕭前史病和[[檢查認識]]結合貝[[形影醫科|𨄴照]]和[[𥌀驗𧖱]]抵類除各可能恪。<ref name="NICE2014Diag">{{chú thích web|title=Dementia diagnosis and assessment|publisher=National Institute for Health and Care Excellence (NICE)|url=http://pathways.nice.org.uk/pathways/dementia/dementia-diagnosis-and-assessment.pdf|access-date=ngày 30 tháng 11 năm 2014|url-status=dead|archive-url=https://web.archive.org/web/20141205184403/http://pathways.nice.org.uk/pathways/dementia/dementia-diagnosis-and-assessment.pdf|archive-date=ngày 5 tháng 12 năm 2014}}</ref>各兆症班頭常被啉貝𧿫號老化通常。<ref name="BMJ2009" />抵診斷病沒格礩振勤沛[[模病學|𥌀驗模腦]]、仍役尼只固體得進行𨍦欺𠊛病㐌死亡。<ref name="NIA2019" />制度[[營養]]合理、運動機體和相作社會—仍要𥯉㐌咮𧡊羅𦀴吏利益對貝過程老化訥終—固體𠢟減少危機衰减認識和安佳𣙪；性𦤾𢆥2019、各試驗臨床當得進行𢗖打價各可能尼。<ref name="NIA2019" />𣗓固茦咍食品識能芇得證明羅固體𫜵減少危機縸病。<ref name="Hsu" /><!-- Kiểm soát -->

現空固方法調治芇固可能垠拯或倒逆演進𧵑病、雖沒數辨法固體暫時改善各兆症。<ref name="WHO2020" /> 𠊛病沛𢭸込事互助𧵑𠊛恪𣈜沒𡗉欣、自𥯉撻挭𨤼𨖲[[𢟙搠𠊛被𠅍智|𠊛𢟙搠𨉟]]。<ref name="Thom2007">{{chú thích tạp chí|vauthors=Thompson CA, Spilsbury K, Hall J, Birks Y, Barnes C, Adamson J|title=Systematic review of information and support interventions for caregivers of people with dementia|journal=BMC Geriatrics|volume=7|page=18|date=July 2007|pmid=17662119|pmc=1951962|doi=10.1186/1471-2318-7-18}}</ref>仍壓力尼固體𦀴性社會、心理、物理和經濟。<ref name="Thom2007" />各章程運動機體固體𦀴吏利益𨕭方面[[生活恆𣈜]]和固潛𨤼改善結果。<ref name="Forb2015">{{chú thích tạp chí|type=Submitted manuscript|vauthors=Forbes D, Forbes SC, Blake CM, Thiessen EJ, Forbes S|title=Exercise programs for people with dementia|journal=The Cochrane Database of Systematic Reviews|volume=132|issue=4|page=CD006489|date=April 2015|pmid=25874613|doi=10.1002/14651858.CD006489.pub4|url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802014000300195}}</ref>各問題衛行為或情狀[[亂神|亂心神]]由𠅍智𨠳𦋦常得調治憑[[茦𢶢亂神]]、仍役尼常空得指定𤳸利益𦀴吏空當計𪚚欺危機死亡𣋽吏高欣。<ref>{{chú thích web|author=National Institute for Health and Clinical Excellence|title=Low-dose antipsychotics in people with dementia|publisher=National Institute for Health and Care Excellence (NICE)|url=https://www.nice.org.uk/advice/ktt7/resources/non-guidance-lowdose-antipsychotics-in-people-with-dementia-pdf|access-date=ngày 29 tháng 11 năm 2014|url-status=dead|archive-url=https://web.archive.org/web/20141205183329/https://www.nice.org.uk/advice/ktt7/resources/non-guidance-lowdose-antipsychotics-in-people-with-dementia-pdf|archive-date=ngày 5 tháng 12 năm 2014}}</ref><ref>{{chú thích web|date=ngày 16 tháng 6 năm 2008|title=Information for Healthcare Professionals: Conventional Antipsychotics|publisher=US Food and Drug Administration|url=https://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124830.htm|access-date=ngày 29 tháng 11 năm 2014|archive-url=https://web.archive.org/web/20141129015823/https://www.fda.gov/drugs/drugsafety/postmarketdrugsafetyinformationforpatientsandproviders/ucm124830.htm|archive-date=ngày 29 tháng 11 năm 2014}}</ref>

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性𦤾𢆥2015、固曠29,8兆𠊛縸安佳𣙪𨕭全世界。<ref name="GBD2015Pre">{{chú thích tạp chí|author=GBD 2015 Disease Injury Incidence Prevalence Collaborators|title=Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015|journal=Lancet|volume=388|issue=10053|pages=1545–1602|date=October 2016|pmid=27733282|pmc=5055577|doi=10.1016/S0140-6736(16)31678-6}}</ref>性𦤾𢆥2020、曠50兆𠊛縸沒𪚚各樣𠅍智。<ref name="WHO2020" />病常起發於仍𠊛自65歲𧿨𨖲、雖然固𦤾10%場合[[病安佳𣙪起發𣋽|起發病𣋽]]欺各兆症出現於度歲自30𦤾60。<ref name="Mend2012">{{chú thích tạp chí|vauthors=Mendez MF|title=Early-onset Alzheimer's disease: nonamnestic subtypes and type 2 AD|journal=Archives of Medical Research|volume=43|issue=8|pages=677–85|date=November 2012|pmid=23178565|pmc=3532551|doi=10.1016/j.arcmed.2012.11.009}}</ref><ref name="NIA2019" />女界縸病𡗉欣男界。<ref>{{Chú thích tạp chí|last=Viña|first=Jose|last2=Lloret|first2=Ana|date=2010|title=Why women have more Alzheimer's disease than men: gender and mitochondrial toxicity of amyloid-beta peptide|url=https://pubmed.ncbi.nlm.nih.gov/20442496/#:~:text=Abstract,longevity%20of%20women%20versus%20men.|journal=Journal of Alzheimer's disease: JAD|volume=20 Suppl 2|pages=S527–533|doi=10.3233/JAD-2010-100501|issn=1875-8908|pmid=20442496}}</ref>病出現於曠6%𠊛自65歲𧿨𨖲。<ref name="BMJ2009" />𢆥2015、悉哿各病𠅍智引𦤾曠1,9兆咔死亡。<ref name="GBD2015De">{{chú thích tạp chí|author=GBD 2015 Mortality Causes of Death Collaborators|title=Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015|journal=Lancet|volume=388|issue=10053|pages=1459–1544|date=October 2016|pmid=27733281|pmc=5388903|doi=10.1016/S0140-6736(16)31012-1}}</ref>病得撻𠸛蹺博士心神和茹病理學{{r|[[阿螺·安佳𣙪]]|Alois Alzheimer}}、𠊛頭先描寫病込𢆥1906。<ref name="pmid9661992" />安佳𣙪羅沒挭𨤼𣁔衛經濟貝社會、相當貝廱疽和病心脈、欺消潠200秭[[都羅美]]𥢅於和旗。<ref name="Hsu" /><ref name="pmid23550670">{{chú thích tạp chí|last1=Hurd|first1=Michael D.|last2=Martorell|first2=Paco|last3=Delavande|first3=Adeline|last4=Mullen|first4=Kathleen J.|last5=Langa|first5=Kenneth M.|title=Monetary Costs of Dementia in the United States|journal=New England Journal of Medicine|date=ngày 4 tháng 4 năm 2013|volume=368|issue=14|pages=1326–1334|doi=10.1056/NEJMsa1204629|pmid=23550670|url=https://pubmed.ncbi.nlm.nih.gov/23550670/|access-date=ngày 30 tháng 3 năm 2021|pmc=3959992}}</ref>

== 讀添 ==

* {{Chú thích sách|title=Alzheimer's Disease: Unraveling the Mystery|url=http://www.nia.nih.gov/Alzheimers/Publications/UnravelingTheMystery|publisher=US Department of Health and Human Services, National Institute on Aging, NIH|year=2008|access-date=ngày 4 tháng 3 năm 2010|archive-date=ngày 1 tháng 10 năm 2008|archive-url=https://web.archive.org/web/20081001171052/http://www.nia.nih.gov/Alzheimers/Publications/UnravelingTheMystery/|url-status=dead}}
* {{Chú thích sách|url=http://www.nia.nih.gov/Alzheimers/Publications/ADPrevented/|title=Can Alzheimer's Disease Be Prevented?|publisher=US Department of Health and Human Services, National Institute on Aging, NIH|year=2009|access-date=ngày 4 tháng 3 năm 2010|archive-date=ngày 3 tháng 12 năm 2010|archive-url=https://web.archive.org/web/20101203184356/http://www.nia.nih.gov/Alzheimers/Publications/ADPrevented/|url-status=dead}}
* {{Chú thích sách|title=Caring for a Person with Alzheimer's Disease: Your Easy-to-Use Guide from the National Institute on Aging|url=http://www.nia.nih.gov/Alzheimers/Publications/CaringAD/|publisher=US Department of Health and Human Services, National Institute on Aging, NIH|year=2009|access-date=ngày 4 tháng 3 năm 2010|archive-date=ngày 3 tháng 12 năm 2010|archive-url=https://web.archive.org/web/20101203173829/http://www.nia.nih.gov/Alzheimers/Publications/CaringAD/|url-status=dead}}
* {{chú thích tạp chí|author=Cummings JL, Frank JC, Cherry D, Kohatsu ND, Kemp B, Hewett L, Mittman B|title=Guidelines for managing Alzheimer's disease: Part I. Assessment|journal=American Family Physician|volume=65|issue=11|pages=2263–2272|year=2002|pmid=12074525|url=http://www.aafp.org/afp/20020601/2263.html|access-date=2010-03-04|archive-date=2008-05-13|archive-url=https://web.archive.org/web/20080513165101/http://www.aafp.org/afp/20020601/2263.html}}
* {{chú thích tạp chí|author=Cummings JL, Frank JC, Cherry D, Kohatsu ND, Kemp B, Hewett L, Mittman B|title=Guidelines for managing Alzheimer's disease: Part II. Treatment|journal=American Family Physician|volume=65|issue=12|pages=2525–2534|year=2002|pmid=12086242|url=http://www.aafp.org/afp/20020615/2525.html|access-date=2010-03-04|archive-date=2008-05-14|archive-url=https://web.archive.org/web/20080514172730/http://www.aafp.org/afp/20020615/2525.html}}
* {{Chú thích web|tiêu đề=Alzheimer’s Behavior Management: Learn to manage common behavior problems|url=http://www.helpguide.org/elder/alzheimers_behavior_problems.htm|tác giả 1=Russell D, Barston S, White M|nhà xuất bản=helpguide.org|ngày tháng=ngày 19 tháng 12 năm 2007|ngày truy cập=ngày 29 tháng 2 năm 2008|archive-date=ngày 23 tháng 2 năm 2008|archive-url=https://web.archive.org/web/20080223082753/http://www.helpguide.org/elder/alzheimers_behavior_problems.htm|url-status=dead}}

== 注釋 ==
{{Tham khảo|colwidth=30em}}

== 連結外 ==
{{thể loại Commons|Alzheimer's disease}}

* [http://www.nia.nih.gov/Alzheimers/ResearchInformation/ResearchCenters/ Alzheimer's Disease Centers (ADCs)] {{Webarchive|url=https://web.archive.org/web/20100604070324/http://www.nia.nih.gov/Alzheimers/ResearchInformation/ResearchCenters/|date=ngày 4 tháng 6 năm 2010}}
* [http://www.nia.nih.gov/alzheimers Alzheimer's Disease Education and Referral (ADEAR) Center]
* [http://www.alz.org/index.asp Alzheimer's Association] {{Webarchive|url=https://web.archive.org/web/20120730181212/http://www.alz.org/index.asp|date=ngày 30 tháng 7 năm 2012}}
* [http://memory.ucsf.edu/ UCSF Memory and Aging Center]
* [http://www.polygenicpathways.co.uk/alzenvrisk.htm Rủi ro môi trường và các yếu tố bảo vệ trong bệnh Alzheimer]